Fertility Care Programme

PreimplantationGenetic
Testing

PGT is a laboratory test performed on IVF embryos before transfer. A handful of cells are biopsied from the outer layer of a day 5–6 blastocyst — the layer that becomes the placenta, not the baby — and sent for genetic analysis while the embryo stays safely frozen. Only embryos that come back genetically normal are thawed and transferred. Day 5–6 Biopsy Stage. 1–2 Weeks Turnaround.

Overview

Understanding Preimplantation Genetic Testing

Preimplantation Genetic Testing checks an embryo's chromosomes before it is transferred. On day five or six of culture, a few cells are taken from the outer layer that will go on to form the placenta — never the part that becomes the baby — and analysed while the embryo waits safely frozen. Only embryos with the correct chromosome count are selected for transfer.

This matters because chromosomal abnormality is the leading cause of embryos failing to implant and of early miscarriage. An embryo can grade beautifully under a microscope and still carry an extra or missing chromosome that makes an ongoing pregnancy impossible. No amount of visual assessment reveals this; only genetic analysis does.

The share of embryos affected climbs steadily with maternal age, which is why PGT comes up most often for women in their late thirties and forties, for couples who have had repeated miscarriages, and for those whose good-looking embryos keep failing to implant. It is also used where a known inherited condition runs in the family.

It is equally important to know what PGT cannot do. It does not improve any embryo — it identifies which of your existing embryos are worth transferring. If every embryo in a cycle tests abnormal, there is no transfer, and that is a difficult but genuinely useful result. What PGT reliably delivers is fewer wasted transfers, a shorter path to a viable pregnancy, and a lower chance of a miscarriage you would otherwise have lived through.

Who This Is For

When To Consider This

Advanced maternal age — chromosomal errors in eggs rise sharply after the mid-30s

Recurrent pregnancy loss, with two or more unexplained miscarriages

Repeated implantation failure despite good-quality embryos

A known genetic condition carried by either partner

A balanced translocation found on karyotype testing

Seek Care Promptly If

  • Severe pelvic pain or bloating during the stimulation phase (possible OHSS)
  • Heavy bleeding after egg retrieval
  • Fever or chills within 48 hours of a procedure

What's Involved

PGT-A — Chromosome Number Screening
PGT-M — Single-Gene Disorder Testing
PGT-SR — Structural Rearrangement Testing
Trophectoderm Biopsy & Vitrification

Expert Video Guides

PGT Explained: Testing Embryos Before Transfer

PGT Explained: Testing Embryos Before Transfer

Motherhood After 4 Years

Motherhood After 4 Years

Questions

Frequently Asked Questions

No. Cells are taken only from the trophectoderm — the outer layer that goes on to form the placenta — not the inner cell mass that becomes the baby.

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